The highest win rate core build is Blackfire Torch, Liandry's Torment, and Shadowflame, which reaches a 53.7% win rate. Most players opt for Blackfire Torch, Shadowflame, and Rabadon's Deathcap, which has a 20.4% pick rate. You should almost always choose Sorcerer's Shoes as your boots, as they are picked in 85.0% of games.

The most effective rune page features Dark Harvest as the primary keystone from the Domination tree, alongside Cheap Shot, Grisly Mementos, and Ultimate Hunter. For your secondary tree, take Sorcery with Axiom Arcanist and Gathering Storm. This specific combination is picked in 27.8% of games.

Karthus Jungle is currently ranked in B tier for Patch 16.2.1. While he is not at the top of the meta, he maintains a solid carry score of 7.1/10. This indicates he can still be a powerful threat in the right hands.

Karthus currently has an overall win rate of 49.2% in the Jungle role. This data is derived from 773 games analyzed in Platinum+ ranked matches. His build-specific win rate matches this figure at 49.2%.

Based on Platinum+ data showing a 49.2% win rate and a difficulty rating of 7/10, Karthus may be challenging for lower elo players. However, his 7.1/10 carry score suggests that if a player masters his kit, they can have a high impact on the game. His low ban rate of 0.4% also makes him easy to pick consistently.

Karthus is a niche pick with a low 1.3% pick rate, suggesting he is mostly played by dedicated enthusiasts. With a B tier ranking and a carry score of 7.1/10, he is worth maining if you enjoy high-damage mages and global pressure. His win rate is stable at 49.2% even without recent buffs.

Karthus sits at a 49.2% win rate, which is fairly balanced for a B tier champion. His performance is likely impacted by his 7/10 difficulty level and the fact that he received no changes in Patch 16.2.1. He remains a situational pick that relies on scaling and hitting skill shots.

Liandry's Torment is the best performing first item with an impressive 61.5% win rate, though it has a low pick rate of 1.7%. It provides excellent synergy with his sustained damage from Defile. Most players start with Blackfire Torch, but Liandry's Torment is statistically more successful.

Karthus is a good pick when your team needs a primary magic damage dealer with a 7.1/10 carry potential. Since his ban rate is only 0.4%, he is rarely taken away from you in the draft. He is particularly effective if you can utilize Exhaust + Smite to win duels or secure kills early.

Karthus spikes hard when he completes his first major item, especially if it is Liandry's Torment which holds a 61.5% win rate. You should focus on maxing Lay Waste first and utilizing your Ultimate Hunter rune to impact the map. Playing around your Dark Harvest stacks and mid-game items like Shadowflame will maximize your damage.

Karthus is strongest in the mid to late game as he scales with items like Rabadon's Deathcap and runes like Gathering Storm. His win rate with a three-item core involving Shadowflame is very respectable, especially the Liandry's Torment variant at 53.7%. His early game relies on safe farming and using Exhaust to survive invades.

Karthus did not receive any direct buffs or nerfs in Patch 16.2.1. Additionally, his core items and runes remained unchanged this patch. His performance has stayed consistent with a 49.2% win rate.

The most successful setup uses Dark Harvest with Sorcery secondary, including Axiom Arcanist and Gathering Storm. While matchups are not specifically detailed, this rune set is the most popular with a 27.8% pick rate. This setup focuses on maximizing your ultimate's uptime and late-game damage regardless of the enemy.